Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 13/20 | 0.51 |
| ▸ | CTSK | P43235 | 11/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6587126 | 0.82 | CTSS (0.75) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6872650 | 0.82 | CTSS (0.75) | CTSSCTSKCTSLCTSB | |
| SCHEMBL20143076 | 0.81 | MEN1 (0.55) | CTSSCTSKCTSLCTSBMEN1 | |
| SCHEMBL16762194 | 0.77 | CTSS (0.46) | CTSSCTSKJAK3BTKMEN1 | |
| SCHEMBL8163276 | 0.77 | JAK3 (0.44) | CTSSCTSKJAK3BTKMEN1 | |
| SCHEMBL6257674 | 0.76 | CTSS (0.61) | CTSSCTSKCTSLCTSBGAA | |
| SCHEMBL6019972 | 0.76 | CTSS (0.51) | CTSSCTSKCTSLCTSB | |
| SCHEMBL7976196 | 0.76 | CTSK (0.43) | CTSSCTSKJAK3BTKMEN1 | |
| SCHEMBL7976200 | 0.76 | CTSK (0.43) | CTSSCTSKJAK3BTKMEN1 | |
| SCHEMBL16762121 | 0.76 | CTSK (0.53) | CTSSCTSKCTSLCTSBJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178958-B1 | N-CYANOMETHYL AMIDES AS PROTEASE INHIBITORS | AXYS PHARM INC (US) | 2004-02-18 | — | — | EP | disclosed |