Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 4/20 | 0.74 |
| ▸ | P2RX1 | P51575 | 5/20 | 0.68 |
| ▸ | GCK | P35557 | 2/20 | 0.57 |
| ▸ | BRAF | P15056 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TMPRSS4 | Q9NRS4 | 5/20 | 0.55 |
| ▸ | JAK2 | O60674 | 1/20 | 0.54 |
| ▸ | JAK1 | P23458 | 1/20 | 0.54 |
| ▸ | TYK2 | P29597 | 1/20 | 0.54 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.53 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6593023 | 0.91 | FADS1 (0.67) | FADS1P2RX1GCKBRAFHDAC1 | |
| SCHEMBL6589803 | 0.87 | FADS1 (0.58) | FADS1P2RX1GCKBRAFHDAC1 | |
| SCHEMBL6594140 | 0.87 | FADS1 (0.72) | FADS1P2RX1BRAFHDAC1ALDH1A1 | |
| SCHEMBL14345139 | 0.87 | FADS1 (0.62) | FADS1P2RX1GCKBRAFHDAC1 | |
| SCHEMBL1351311 | 0.86 | FADS1 (0.57) | FADS1P2RX1BRAFHDAC1 | |
| SCHEMBL10243995 | 0.86 | FADS1 (0.57) | FADS1P2RX1BRAFHDAC1 | |
| SCHEMBL3810890 | 0.85 | FADS1 (0.60) | FADS1P2RX1GCKALDH1A1POLB | |
| SCHEMBL491775 | 0.83 | FADS1 (0.58) | FADS1P2RX1GCKBRAFHDAC1 | |
| SCHEMBL1961988 | 0.83 | FADS1 (0.73) | FADS1P2RX1ALDH1A1TMPRSS4 | |
| SCHEMBL6590611 | 0.82 | NPC1 (0.58) | FADS1P2RX1BRAFHDAC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1143855-C | I (ortho)-anthranilamide derivatives as anti-coagulants | ���ֹɷݹ�˾ | 2004-03-31 | — | — | CN | disclosed |
| EP-1040108-B1 | ORTHO-ANTHRANILAMIDE DERIVATIVES AS ANTI-COAGULANTS | SCHERING AG (DE) | 2004-02-25 | — | — | EP | disclosed |
| US-6498185-B1 | ENZYME FACTOR XA INHIBITORS | BERLEX LABORATORIES, INC. | 2002-12-24 | — | — | US | disclosed |
| US-6380221-B1 | FOR THERAPY OF DISEASE-STATES CHARACTERIZED BY THROMBOTIC ACTIVITY | BERLEX LABORATORIES, INC. | 2002-04-30 | — | — | US | disclosed |
| CN-1282329-A | I (ortho)-anthranilamide derivatives as anti-coagulants | SCHERING AG (DE) | 2001-01-31 | — | — | CN | disclosed |
| US-6140351-A | FOR TREATING THROMBOSIS | BERLEX LABORATORIES, INC. (US) | 2000-10-31 | — | — | US | disclosed |