Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 4/20 | 0.72 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.52 |
| ▸ | BRAF | P15056 | 2/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | F10 | P00742 | 2/20 | 0.50 |
| ▸ | PNLIP | P16233 | 1/20 | 0.48 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6593295 | 0.88 | P2RX1 (0.58) | FADS1P2RX1RAB9ANPC1ALDH1A1 | |
| SCHEMBL6587131 | 0.87 | FADS1 (0.74) | FADS1P2RX1ALDH1A1LMNAHDAC1 | |
| SCHEMBL12885792 | 0.84 | FADS1 (0.72) | FADS1P2RX1RAB9ANPC1ALDH1A1 | |
| SCHEMBL6590611 | 0.83 | NPC1 (0.58) | FADS1P2RX1RAB9ANPC1ALDH1A1 | |
| SCHEMBL3157341 | 0.82 | RAB9A (0.61) | FADS1RAB9ANPC1ALDH1A1LMNA | |
| SCHEMBL6589803 | 0.82 | FADS1 (0.58) | FADS1P2RX1KMT2AMAPK1HDAC1 | |
| SCHEMBL5222830 | 0.81 | BRAF (0.59) | FADS1RAB9ANPC1KMT2ASMN1; SMN2 | |
| SCHEMBL10243995 | 0.81 | FADS1 (0.57) | FADS1P2RX1KMT2AHDAC1BRAF | |
| SCHEMBL1351311 | 0.81 | FADS1 (0.57) | FADS1P2RX1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6593129 | 0.81 | FADS1 (0.60) | FADS1P2RX1RAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1143855-C | I (ortho)-anthranilamide derivatives as anti-coagulants | ���ֹɷݹ�˾ | 2004-03-31 | — | — | CN | disclosed |
| EP-1040108-B1 | ORTHO-ANTHRANILAMIDE DERIVATIVES AS ANTI-COAGULANTS | SCHERING AG (DE) | 2004-02-25 | — | — | EP | disclosed |
| US-6498185-B1 | ENZYME FACTOR XA INHIBITORS | BERLEX LABORATORIES, INC. | 2002-12-24 | — | — | US | disclosed |
| US-6380221-B1 | FOR THERAPY OF DISEASE-STATES CHARACTERIZED BY THROMBOTIC ACTIVITY | BERLEX LABORATORIES, INC. | 2002-04-30 | — | — | US | disclosed |
| CN-1282329-A | I (ortho)-anthranilamide derivatives as anti-coagulants | SCHERING AG (DE) | 2001-01-31 | — | — | CN | disclosed |
| US-6140351-A | FOR TREATING THROMBOSIS | BERLEX LABORATORIES, INC. (US) | 2000-10-31 | — | — | US | disclosed |