Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 16/20 | 0.80 |
| ▸ | PDE4D | Q08499 | 15/20 | 0.80 |
| ▸ | PDE4A | P27815 | 11/20 | 0.80 |
| ▸ | PDE4C | Q08493 | 11/20 | 0.80 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7329999 | 0.92 | PDE4D (0.80) | PDE4BPDE4DPDE4APDE4CMAPK14 | |
| SCHEMBL6585967 | 0.87 | PDE4B (0.65) | PDE4BPDE4DPDE4APDE4CMAPK14 | |
| SCHEMBL5349155 | 0.86 | PDE4B (0.67) | PDE4BPDE4DPDE4APDE4CMAPK14 | |
| SCHEMBL29670763 | 0.84 | CTNNB1 (0.67) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL4861157 | 0.84 | CTNNB1 (0.67) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL131830 | 0.83 | PDE4B (0.64) | PDE4BPDE4DPDE4APDE4CMAPK14 | |
| SCHEMBL5565347 | 0.83 | PDE4B (0.64) | PDE4BPDE4DPDE4APDE4CMAPK14 | |
| SCHEMBL4709683 | 0.82 | PDE4B (0.65) | PDE4BPDE4DPDE4APDE4CMAPK14 | |
| SCHEMBL7332246 | 0.82 | PDE4B (0.75) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL27472680 | 0.81 | PDE4D (0.68) | PDE4BPDE4DPDE4APDE4CMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0928789-B1 | 6-PHENYLTETRAHYDRO-1,3-OXAZIN-2-ONE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2004-09-29 | — | — | EP | disclosed |
| US-6251897-B1 | TREATING DERMATITIS, ASTHMA | NIKKEN CHEMICALS CO., LTD (JP) | 2001-06-26 | — | — | US | disclosed |
| EP-0928789-A1 | 6-PHENYLTETRAHYDRO-1,3-OXAZIN-2-ONE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-07-14 | — | — | EP | disclosed |