Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 12/20 | 0.34 |
| ▸ | CA2 | P00918 | 12/20 | 0.34 |
| ▸ | CA9 | Q16790 | 10/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.32 |
| ▸ | CA7 | P43166 | 3/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.32 |
| ▸ | CA3 | P07451 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | CA6 | P23280 | 2/20 | 0.32 |
| ▸ | CA5A | P35218 | 2/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6587440 | 1.00 | TSHR (0.56) | TSHRALDH1A1USP2KDM4ELMNA | |
| SCHEMBL5636350 | 0.87 | USP2 (0.48) | TSHRALDH1A1USP2KDM4ELMNA | |
| SCHEMBL8064670 | 0.87 | USP2 (0.48) | TSHRALDH1A1USP2KDM4ELMNA | |
| SCHEMBL10624042 | 0.82 | TSHR (0.50) | TSHRALDH1A1USP2KDM4ELMNA | |
| SCHEMBL13056219 | 0.82 | FNTA (0.35) | TSHRALDH1A1USP2KDM4ELMNA | |
| SCHEMBL10081545 | 0.81 | LMNA (0.65) | TSHRALDH1A1USP2KDM4ELMNA | |
| SCHEMBL4082038 | 0.80 | ALDH1A1 (0.64) | TSHRALDH1A1USP2KDM4ELMNA | |
| SCHEMBL5789924 | 0.79 | KDM4E (0.50) | TSHRALDH1A1USP2KDM4ELMNA | |
| SCHEMBL5789812 | 0.79 | TSHR (0.56) | TSHRALDH1A1USP2KDM4ELMNA | |
| SCHEMBL365926 | 0.78 | CA1 (0.39) | TSHRALDH1A1USP2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0823423-B1 | 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-06-16 | — | — | EP | disclosed |
| US-5750540-A | SIDE EFFECT REDUCTION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0823423-A1 | 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-02-11 | — | — | EP | disclosed |