Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 15/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 12/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4918994 | 0.84 | OPRL1 (0.57) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL4918957 | 0.82 | OPRL1 (0.52) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL6590145 | 0.80 | CHRM2 (0.46) | OPRL1OPRM1OPRK1KDM4EALDH1A1 | |
| SCHEMBL4919830 | 0.75 | OPRL1 (0.69) | OPRL1OPRM1OPRK1TACR1KDM4E | |
| SCHEMBL4916510 | 0.75 | OPRL1 (0.53) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL8128346 | 0.75 | OPRM1 (0.49) | OPRL1OPRM1OPRK1KDM4EALDH1A1 | |
| SCHEMBL6582289 | 0.74 | OPRL1 (0.59) | OPRL1OPRM1OPRK1TACR1OPRD1 | |
| SCHEMBL4920073 | 0.71 | OPRL1 (0.65) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL4919777 | 0.71 | OPRL1 (0.51) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL4913219 | 0.70 | OPRL1 (0.53) | OPRL1OPRM1OPRK1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990653-B1 | 2-OXOIMIDAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-6258825-B1 | ANALGESIC, A RELIEVER AGAINST TOLERANCE TO A NARCOTIC ANALGESIC REPRESENTED BY MORPHINE, REMEDY FOR PARKINSONISM, A REMEDY FOR CHOREA, AN ANTIDEPRESSANT, A REMEDY FOR DIABETES INSIPIDUS, A REMEDY FOR POLYURIA, OR HYPOTENSION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0990653-A1 | 2-OXOIMIDAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-04-05 | — | — | EP | disclosed |