Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | SLC18A2 | Q05940 | 9/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6586061 | 0.84 | OPRL1 (0.58) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL4916517 | 0.84 | OPRL1 (0.58) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL4918766 | 0.83 | OPRL1 (0.48) | CHRM2CHRM4CHRM1CHRM3OPRL1 | |
| SCHEMBL6586718 | 0.82 | OPRM1 (0.57) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL6587465 | 0.80 | OPRL1 (0.40) | OPRL1OPRM1OPRK1KDM4EALDH1A1 | |
| SCHEMBL7744376 | 0.79 | OPRL1 (0.56) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL7746945 | 0.79 | OPRL1 (0.56) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL4919083 | 0.79 | OPRM1 (0.62) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL6585954 | 0.78 | OPRL1 (0.51) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL8658891 | 0.76 | CHRM1 (0.55) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990653-B1 | 2-OXOIMIDAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-6258825-B1 | ANALGESIC, A RELIEVER AGAINST TOLERANCE TO A NARCOTIC ANALGESIC REPRESENTED BY MORPHINE, REMEDY FOR PARKINSONISM, A REMEDY FOR CHOREA, AN ANTIDEPRESSANT, A REMEDY FOR DIABETES INSIPIDUS, A REMEDY FOR POLYURIA, OR HYPOTENSION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0990653-A1 | 2-OXOIMIDAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-04-05 | — | — | EP | disclosed |