Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.53 |
| ▸ | GSK3A | P49840 | 2/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.53 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.53 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.53 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.53 |
| ▸ | PRKCG | P05129 | 1/20 | 0.53 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.53 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.53 |
| ▸ | BRSK1 | Q8TDC3 | 1/20 | 0.53 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.53 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.43 |
| ▸ | MARK3 | P27448 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7762876 | 0.95 | PIM1 (0.46) | PIM1GSK3ADYRK1APIM3AURKB | |
| Hydrochloric Acid SCHEMBL6585041 | 0.94 | PIM1 (0.45) | PIM1GSK3ADYRK1APIM3AURKB | |
| SCHEMBL6590811 | 0.91 | PIM1 (0.42) | PIM1GSK3ADYRK1APIM3AURKB | |
| SCHEMBL6587470 | 0.88 | PDE5A (0.43) | PIM1GSK3ADYRK1APIM3AURKB | |
| SCHEMBL6809666 | 0.87 | PIM1 (0.70) | PIM1GSK3ADYRK1APIM3AURKB | |
| SCHEMBL6591529 | 0.83 | PIM1 (0.75) | PIM1GSK3ADYRK1APIM3AURKB | |
| SCHEMBL7764199 | 0.83 | PIM1 (0.55) | PIM1GSK3ADYRK1APIM3AURKB | |
| SCHEMBL6591524 | 0.82 | AURKB (0.55) | PIM1GSK3ADYRK1APIM3AURKB | |
| Hydrochloric Acid SCHEMBL6587717 | 0.82 | PIM1 (0.54) | PIM1GSK3ADYRK1APIM3AURKB | |
| SCHEMBL6585926 | 0.82 | PIM1 (0.47) | PIM1GSK3ADYRK1APIM3AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177178-B1 | HETEROCYCLICALLY SUBSTITUTED BENZIMIDAZOLES, THE PRODUCTION AND APPLICATION THEREOF | ABBOTT GMBH & CO KG (DE) | 2004-12-29 | — | — | EP | disclosed |
| WO-2001082877-A2 | USE OF PARP INHIBITORS IN COSMETIC PREPARATIONS | BASF AKTIENGESELLSCHAFT (DE) | 2001-11-08 | — | — | WO | disclosed |