Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 4/20 | 0.70 |
| ▸ | GSK3A | P49840 | 4/20 | 0.70 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.70 |
| ▸ | PIM3 | Q86V86 | 4/20 | 0.70 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.70 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.70 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.70 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.70 |
| ▸ | BRSK1 | Q8TDC3 | 2/20 | 0.70 |
| ▸ | PRKCG | P05129 | 1/20 | 0.70 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.70 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.70 |
| ▸ | CLK2 | P49760 | 3/20 | 0.55 |
| ▸ | PRKD2 | Q9BZL6 | 3/20 | 0.55 |
| ▸ | STK17A | Q9UEE5 | 3/20 | 0.55 |
| ▸ | KDR | P35968 | 2/20 | 0.55 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.55 |
| ▸ | PHKG2 | P15735 | 2/20 | 0.55 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.55 |
| ▸ | LCK | P06239 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6803487 | 0.94 | PIM1 (0.61) | PIM1GSK3ADYRK1APIM3AURKB | |
| SCHEMBL6799871 | 0.91 | PIM1 (0.57) | PIM1GSK3ADYRK1APIM3AURKB | |
| SCHEMBL6587676 | 0.87 | PIM1 (0.53) | PIM1GSK3ADYRK1APIM3AURKB | |
| SCHEMBL6809679 | 0.85 | GSK3A (0.51) | PIM1GSK3ADYRK1APIM3AURKB | |
| SCHEMBL6806635 | 0.82 | PIM1 (1.00) | PIM1GSK3ADYRK1APIM3AURKB | |
| SCHEMBL6805747 | 0.81 | AURKB (0.71) | PIM1GSK3ADYRK1APIM3AURKB | |
| Hydrochloric Acid SCHEMBL6806554 | 0.81 | PIM1 (0.69) | PIM1GSK3ADYRK1APIM3AURKB | |
| SCHEMBL6799720 | 0.81 | PIM1 (0.71) | PIM1GSK3ADYRK1APIM3AURKB | |
| SCHEMBL6807413 | 0.81 | AURKB (0.62) | PIM1GSK3ADYRK1APIM3AURKB | |
| SCHEMBL7762876 | 0.81 | PIM1 (0.46) | PIM1GSK3ADYRK1APIM3AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696437-B1 | Heterocyclically substituted benzimidazoles, the production and application thereof | ABBOTT GMBH & CO. KG (DE) | 2004-02-24 | — | — | US | disclosed |