SCHEMBL9418352

SCHEMBL9418352

C=C(C)C(=O)OC(CC)[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5837859 0.98 TSHR (0.33) TSHRTHRB
SCHEMBL65879 0.94 TSHR (0.35) TSHRTHRB
SCHEMBL8167214 0.86 TSHR (0.33) TSHRTHRB
SCHEMBL4972445 0.86 TSHR (0.33) TSHRTHRB
Glycerin SCHEMBL2138419 0.85 TSHR (0.30) TSHR
SCHEMBL4884446 0.84 TSHR (0.32) TSHR
Tromethamine SCHEMBL1969065 0.83
SCHEMBL9578367 0.82
SCHEMBL1273966 0.81 TSHR (0.35) TSHRTHRB
SCHEMBL10941021 0.81 TSHR (0.35) TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11866531-B2 Oil-resistant lens material and ophthalmic devices Twenty Twenty Therapeutrics LLC (US) 2024-01-09 US disclosed
WO-2021067189-A1 OIL-RESISTANT LENS MATERIAL AND ELECTROWETTING OPHTHALMIC DEVICES VERILY LIFE SCIENCES LLC (US) 2021-04-08 WO disclosed
US-20210095063-A1 OIL-RESISTANT LENS MATERIAL AND OPHTHALMIC DEVICES VERILY LIFE SCIENCES LLC 2021-04-01 US disclosed
US-10752833-B2 Optical element for correcting color blindness NITTO DENKO CORPORATION (JP) 2020-08-25 US disclosed
CN-104024891-B For correcting the optical element of colour blindness 日东电工株式会社 2019-06-28 CN disclosed
US-20190194535-A1 OPTICAL ELEMENT FOR CORRECTING COLOR BLINDNESS NITTO DENKO CORPORATION (JP) 2019-06-27 US disclosed
US-10119070-B2 Optical element for correcting color blindness NITTO DENKO CORPORATION (JP) 2018-11-06 US disclosed
US-9885883-B2 Optical element for correcting color blindness NITTO DENKO CORPORATION (JP) 2018-02-06 US disclosed
US-20170088771-A1 OPTICAL ELEMENT FOR CORRECTING COLOR BLINDNESS NITTO DENKO CORPORATION (JP) 2017-03-30 US disclosed
EP-2951620-B1 OPTICAL ELEMENT FOR CORRECTING COLOR BLINDNESS NITTO DENKO CORP (JP) 2017-03-01 EP disclosed
US-20130062564-A1 Optical Element for Correcting Color Blindness NITTO DENKO CORPORATION (JP) 2013-03-14 US disclosed
US-20130057824-A1 Optical Element for Correcting Color Blindness NITTO DENKO CORPORATION (JP) 2013-03-07 US disclosed
US-20130056682-A1 Optical Element for Correcting Color Blindness NITTO DENKO CORPORATION (JP) 2013-03-07 US disclosed
WO-2013022744-A2 OPTICAL ELEMENT FOR CORRECTING COLOR BLINDNESS NITTO DENKO CORPORATION (JP) 2013-02-14 WO disclosed
US-20130033776-A1 Optical Element for Correcting Color Blindness NITTO DENKO CORPORATION (JP) 2013-02-07 US disclosed
US-20130032758-A1 Optical Element for Correcting Color Blindness NITTO DENKO CORPORATION (JP) 2013-02-07 US disclosed
EP-0294515-B1 Contact lens material MENICON CO LTD (JP) 1994-05-25 EP disclosed
US-4814402-A VINYLPYRROLIDONE OR METHACRYLIC ACID AND SILICON CONTAINING METHACRYLATE MENICON CO., LTD. (JP) 1989-03-21 US disclosed
US-4594401-A Oxygen permeable hard contact lens formed from styrene monomer containing a silyl or siloxane group SHIN-ETSU CHEMICAL CO., LTD. (JP) 1986-06-10 US disclosed
US-4433125-A COPOLYMER OF SILICON CONTAINING ACRYLATE OR METHACRYLATE, AND FLUOROALKYL ACRYLATE OR METHACRYLATE SHIN-ETSU CHEMICAL CO., LTD. (JP) 1984-02-21 US disclosed