Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORD | Q00796 | 15/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6585270 | 1.00 | SORD (1.00) | SORDKDM4EMEN1KMT2ASUV39H2 | |
| SCHEMBL6585040 | 0.86 | SORD (0.76) | SORDKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL6586568 | 0.85 | SORD (1.00) | SORD | |
| SCHEMBL6585366 | 0.85 | SORD (1.00) | SORD | |
| SCHEMBL6585364 | 0.85 | SORD (1.00) | SORD | |
| SCHEMBL6584718 | 0.82 | SORD (0.69) | SORD | |
| SCHEMBL7588700 | 0.78 | SORD (0.68) | SORDKDM4EMEN1KMT2ASUV39H2 | |
| SCHEMBL9450503 | 0.77 | SORD (0.74) | SORDKDM4EMEN1KMT2ASUV39H2 | |
| Hydrochloric Acid SCHEMBL9450505 | 0.76 | SORD (0.72) | SORDKDM4EMEN1KMT2ASUV39H2 | |
| SCHEMBL6587390 | 0.75 | SORD (0.64) | SORDKDM4EMEN1KMT2ASUV39H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041068-B1 | Compounds for treating and preventing diabetic complications | PFIZER PROD INC (US) | 2004-04-14 | — | — | EP | disclosed |
| US-6294538-B1 | ANTIDIABETIC AGENTS AND DIABETIC NEUROPATHY, TREATMENT WITH OXIDOREDUCTASE ENZYMES | PFIZER INC. | 2001-09-25 | — | — | US | disclosed |
| EP-1041068-A1 | Compounds for treating and preventing diabetic complications | Pfizer Products Inc. (US) | 2000-10-04 | — | — | EP | disclosed |