Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORD | Q00796 | 12/20 | 0.74 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9450505 | 0.99 | SORD (0.72) | SORDTLR9TLR7MEN1KMT2A | |
| SCHEMBL29941725 | 0.85 | SORD (1.00) | SORD | |
| SCHEMBL7047595 | 0.85 | SORD (1.00) | SORD | |
| SCHEMBL6293374 | 0.84 | SORD (0.52) | SORDMEN1KMT2AKDM4E | |
| SCHEMBL7588700 | 0.79 | SORD (0.68) | SORDMEN1KMT2AKDM4ESUV39H2 | |
| SCHEMBL10569550 | 0.79 | SORD (0.54) | SORD | |
| SCHEMBL10564194 | 0.77 | SORD (0.53) | SORD | |
| SCHEMBL6587912 | 0.77 | SORD (1.00) | SORDMEN1KMT2AKDM4ESUV39H2 | |
| SCHEMBL6585270 | 0.77 | SORD (1.00) | SORDMEN1KMT2AKDM4ESUV39H2 | |
| SCHEMBL6587390 | 0.76 | SORD (0.64) | SORDMEN1KMT2AKDM4ESUV39H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5215990-A | Screening for aldose reductase inhibitors | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-01 | — | — | US | disclosed |
| EP-0470616-A2 | Substituted pyrimidin derivatives, process for their preparation and their use as reagent | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-12 | — | — | EP | disclosed |