Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 14/20 | 0.57 |
| ▸ | MMP3 | P08254 | 14/20 | 0.57 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.41 |
| ▸ | CDK9 | P50750 | 3/20 | 0.41 |
| ▸ | CTPS1 | P17812 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582915 | 0.89 | MMP2 (0.72) | MMP2MMP3CCNT1CDK9MMP1 | |
| SCHEMBL6590755 | 0.82 | MMP2 (0.52) | MMP2MMP3CCNT1CDK9MMP1 | |
| SCHEMBL6586244 | 0.81 | MMP2 (0.49) | MMP2MMP3 | |
| SCHEMBL6439725 | 0.81 | MMP2 (0.62) | MMP2MMP3CCNT1CDK9MMP1 | |
| SCHEMBL6590027 | 0.81 | MMP2 (0.61) | MMP2MMP3CCNT1CDK9MMP1 | |
| SCHEMBL6590101 | 0.80 | MMP2 (0.65) | MMP2MMP3CTPS1MMP1MMP9 | |
| SCHEMBL6584020 | 0.80 | MMP2 (0.72) | MMP2MMP3CCNT1CDK9MMP1 | |
| SCHEMBL6586191 | 0.80 | MMP2 (0.76) | MMP2MMP3CCNT1CDK9MMP1 | |
| SCHEMBL6584515 | 0.80 | MMP2 (0.59) | MMP2MMP3CCNT1CDK9MMP1 | |
| SCHEMBL6437646 | 0.77 | MMP2 (0.48) | MMP2MMP3CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036062-B1 | HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE (MMP) INHIBITORS | PFIZER LTD (GB) | 2004-01-02 | — | — | EP | disclosed |
| US-6495568-B1 | TREATMENT OF TISSUE ULCERATION, WOUND REPAIR AND SKIN DISEASES | WARNER-LAMBERT COMPANY | 2002-12-17 | — | — | US | disclosed |