Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 11/20 | 0.49 |
| ▸ | MMP3 | P08254 | 11/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | POLQ | O75417 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6586466 | 0.91 | MMP2 (0.51) | MMP2MMP3EPHX2L3MBTL1EGLN1 | |
| SCHEMBL6590943 | 0.90 | MMP2 (0.54) | MMP2MMP3 | |
| SCHEMBL6588048 | 0.81 | MMP2 (0.57) | MMP2MMP3 | |
| SCHEMBL6586391 | 0.80 | MMP2 (0.47) | MMP2MMP3 | |
| SCHEMBL6582915 | 0.79 | MMP2 (0.72) | MMP2MMP3 | |
| SCHEMBL6590755 | 0.79 | MMP2 (0.52) | MMP2MMP3HTR1A | |
| SCHEMBL6590027 | 0.78 | MMP2 (0.61) | MMP2MMP3 | |
| SCHEMBL6437646 | 0.78 | MMP2 (0.48) | MMP2MMP3L3MBTL1 | |
| SCHEMBL6587603 | 0.77 | MMP2 (0.48) | MMP2MMP3L3MBTL1 | |
| SCHEMBL6587154 | 0.76 | MMP2 (0.52) | MMP2MMP3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036062-B1 | HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE (MMP) INHIBITORS | PFIZER LTD (GB) | 2004-01-02 | — | — | EP | disclosed |
| US-6495568-B1 | TREATMENT OF TISSUE ULCERATION, WOUND REPAIR AND SKIN DISEASES | WARNER-LAMBERT COMPANY | 2002-12-17 | — | — | US | disclosed |