Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 19/20 | 0.35 |
| ▸ | CTSS | P25774 | 9/20 | 0.35 |
| ▸ | CTSL | P07711 | 8/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6590445 | 0.92 | CTSK (0.32) | CTSKCTSSCTSLPOLBHSD17B10 | |
| SCHEMBL6590159 | 0.90 | CTSL (0.42) | CTSKCTSSCTSL | |
| SCHEMBL6586706 | 0.88 | CTSK (0.33) | CTSKCTSSCTSLPOLBHSD17B10 | |
| SCHEMBL6593240 | 0.86 | CTSK (0.45) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6588604 | 0.86 | CTSK (0.38) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6594578 | 0.86 | CTSL (0.34) | CTSKCTSSCTSL | |
| SCHEMBL6589081 | 0.85 | CTSL (0.34) | CTSKCTSSCTSL | |
| SCHEMBL6486103 | 0.84 | POLB (0.44) | CTSKCTSSCTSLPOLBHSD17B10 | |
| SCHEMBL6586665 | 0.84 | CTSL (0.40) | CTSKCTSSCTSL | |
| SCHEMBL6594928 | 0.83 | CTSK (0.35) | CTSKCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178986-B1 | FURANONE DERIVATIVES AS INHIBITORS OF CATHEPSIN S | MEDIVIR UK LTD (GB) | 2004-02-25 | — | — | EP | claimed |