SCHEMBL6589306

SCHEMBL6589306

CC1CC(c2cc(Br)c(O)c(C(C)C)c2)CC(C)(C)C1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.36
GABRB1 P18505 1/20 0.36
ALDH1A1 P00352 1/20 0.31
HTT P42858 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
GGPS1 O95749 1/20 0.30
FDPS P14324 1/20 0.30
GLRA1 P23415 1/20 0.30
IDH1 O75874 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6589305 1.00 GABRA1 (0.36) GABRA1GABRB1ALDH1A1HTTCA1
SCHEMBL6607441 0.90 CA1 (0.39) GABRA1GABRB1ALDH1A1CA1CA2
SCHEMBL6607439 0.90 CA1 (0.39) GABRA1GABRB1ALDH1A1CA1CA2
SCHEMBL6589192 0.87 ALDH1A1 (0.35) ALDH1A1HTT
SCHEMBL6589188 0.87 ALDH1A1 (0.35) ALDH1A1HTT
SCHEMBL6589099 0.84 GABRA1 (0.36) GABRA1GABRB1CA1CA2
SCHEMBL6589096 0.84 GABRA1 (0.36) GABRA1GABRB1CA1CA2
SCHEMBL7128533 0.84 GABRA1 (0.30) GABRA1GABRB1
SCHEMBL6592597 0.82 ALDH1A1 (0.33) ALDH1A1HTT
SCHEMBL6592593 0.82 ALDH1A1 (0.33) ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113166500-A Polyethylene with additives for increasing environmental stress crack resistance SABIC环球技术有限责任公司 2021-07-23 CN disclosed
CN-108463481-B Method for producing polycarbonate 国际壳牌研究有限公司 2021-04-09 CN disclosed
CN-112313277-A Polyethylene with polycarbonate-siloxane for improved environmental stress crack resistance SABIC环球技术有限责任公司 2021-02-02 CN disclosed
CN-108473672-B Process for preparing melt polycarbonate 国际壳牌研究有限公司 2020-12-08 CN disclosed
CN-101796109-B Polymer foam having nanocellular morphology and method of making same SABIC INNOVATIVE PLASTICS IP 2012-12-26 CN disclosed
CN-102775752-A Polymeric foams with nanocellular morphology and methods for making them SABIC INNOVATIVE PLASTICS IP 2012-11-14 CN disclosed
CN-102516518-A Method of preparing polycarbonate SABIC INNOVATIVE PLASTICS IP 2012-06-27 CN disclosed
CN-101472995-B Polycarbonate compositions and articles formed therefrom SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-12-28 CN disclosed
CN-101479315-B Preparation of polycarbonates SABIC INNOVATIVE PLASTICS IP 2011-09-14 CN disclosed
CN-101056913-B Process to make polycarbonate from bismethylsalicylcarbonate (BMSC) SABIC INNOVATIVE PLASTICS IP 2011-09-14 CN disclosed
CN-101331169-A Equipment cleaning in polycarbonate manufacture GEN ELECTRIC (US) 2008-12-24 CN disclosed
CN-101056913-A Process to make polycarbonate from bismethylsalicylcarbonate (BMSC) GEN ELECTRIC (US) 2007-10-17 CN disclosed
CN-1972982-A Method for preparing a polycarbonate oligomer mixture at low temperature for manufacturing polycarbonate GEN ELECTRIC (US) 2007-05-30 CN disclosed
CN-1914248-A Process for the production of copolycarbonates with reduced color GEN ELECTRIC (US) 2007-02-14 CN disclosed
CN-1694914-A Method and apparatus for preparing high molecular weight melt polycarbonate GEN ELECTRIC (US) 2005-11-09 CN disclosed
EP-1414888-A1 EXTRUSION METHOD FOR MAKING POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2004-05-06 EP disclosed
EP-1414887-A1 METHOD OF POLYCARBONATE PREPARATION GENERAL ELECTRIC COMPANY (US) 2004-05-06 EP disclosed
WO-2003010220-A1 EXTRUSION METHOD FOR MAKING POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2003-02-06 WO disclosed
WO-2003010218-A1 METHOD OF POLYCARBONATE PREPARATION GENERAL ELECTRIC COMPANY (US) 2003-02-06 WO disclosed
CN-1383450-A Antibody molecule with specificity to human tumor necrosis factor alpha and application thereof CELLTECH R&D LTD (GB) 2002-12-04 CN disclosed