Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7412495 | 0.93 | MAOB (0.39) | MAOBKDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL6585338 | 0.81 | ENPP2 (0.41) | LMNA | |
| SCHEMBL6589307 | 0.74 | MAOB (0.38) | MAOBKDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL7411096 | 0.74 | ENPP2 (0.34) | LMNA | |
| SCHEMBL23363494 | 0.72 | MAOB (0.47) | MAOBKDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL29934083 | 0.72 | MAOB (0.47) | MAOBKDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL8796366 | 0.71 | IDO1 (0.42) | MAOBALDH1A1KMT2A | |
| SCHEMBL6294536 | 0.71 | MAOB (0.50) | MAOBKDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL706845 | 0.71 | KCNH2 (0.33) | ALDH1A1LMNAKMT2AGAA | |
| SCHEMBL28549733 | 0.70 | MEN1 (0.30) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036062-B1 | HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE (MMP) INHIBITORS | PFIZER LTD (GB) | 2004-01-02 | — | — | EP | disclosed |
| US-6495568-B1 | TREATMENT OF TISSUE ULCERATION, WOUND REPAIR AND SKIN DISEASES | WARNER-LAMBERT COMPANY | 2002-12-17 | — | — | US | disclosed |