Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.45 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetone SCHEMBL27641890 | 0.88 | TSHR (0.50) | TSHRALDH1A1SMN1; SMN2MYCESR1 | |
| Acetic Acid SCHEMBL27497245 | 0.88 | TSHR (0.50) | TSHRALDH1A1SMN1; SMN2MYCESR1 | |
| SCHEMBL69633 | 0.87 | TSHR (0.53) | TSHRALDH1A1SMN1; SMN2MYCESR1 | |
| SCHEMBL1669169 | 0.87 | CYP2A6 (0.48) | SMN1; SMN2AKR1C3AKR1C2TDP1RAB9A | |
| SCHEMBL10936859 | 0.85 | TSHR (0.52) | TSHRALDH1A1SMN1; SMN2MYCESR1 | |
| SCHEMBL11664352 | 0.85 | TSHR (0.52) | TSHRALDH1A1SMN1; SMN2MYCESR1 | |
| SCHEMBL28858438 | 0.85 | TSHR (0.52) | TSHRALDH1A1SMN1; SMN2MYCESR1 | |
| Hydrochloric Acid SCHEMBL10448118 | 0.85 | TSHR (0.52) | TSHRALDH1A1SMN1; SMN2MYCESR1 | |
| Hydrochloric Acid SCHEMBL16610510 | 0.85 | TSHR (0.52) | TSHRALDH1A1SMN1; SMN2MYCESR1 | |
| Benzene SCHEMBL27546363 | 0.85 | KDM4E (0.55) | TSHRALDH1A1SMN1; SMN2MYCESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116621899-A | Unnatural nucleoside analogues and uses thereof | 中国人民解放军军事科学院军事医学研究院 | 2023-08-22 | — | — | CN | disclosed |
| CN-102712615-A | Chromenone Derivatives with Antitumor Activity | ASTRAZENECA AB | 2012-10-03 | — | — | CN | disclosed |
| EP-1150977-B1 | PHENYL UREA AND PHENYL THIOUREA DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 2004-08-25 | — | — | EP | disclosed |
| US-6699879-B1 | OBESITY, DIABETES, SLEEP DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 2004-03-02 | — | — | US | disclosed |
| EP-1150977-A1 | PHENYL UREA AND PHENYL THIOUREA DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 2001-11-07 | — | — | EP | disclosed |
| CN-1068308-C | Substituted benzoylguanide preparation and pharmaceutical application of same | HOECHST AG (DE) | 2001-07-11 | — | — | CN | disclosed |
| WO-2000047577-A1 | PHENYL UREA AND PHENYL THIOUREA DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 2000-08-17 | — | — | WO | disclosed |
| CN-1132745-A | Substituted henzoylguanidines, process for their preparation, their use as medicament or diagnostic, and medicament containing them | HOECHST AG (DE) | 1996-10-09 | — | — | CN | disclosed |
| CN-1097737-A | Benzoyl guanidine, its method for making that replaces and contain their medicine and application | HOECHST AG (DE) | 1995-01-25 | — | — | CN | disclosed |