Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 18/20 | 0.39 |
| ▸ | CTSK | P43235 | 18/20 | 0.39 |
| ▸ | CTSS | P25774 | 17/20 | 0.39 |
| ▸ | HRH2 | P25021 | 2/20 | 0.32 |
| ▸ | HRH1 | P35367 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6591052 | 0.93 | CTSL (0.46) | CTSLCTSKCTSS | |
| SCHEMBL6590369 | 0.91 | CTSL (0.41) | CTSLCTSKCTSS | |
| SCHEMBL6590400 | 0.90 | CTSL (0.49) | CTSLCTSKCTSS | |
| SCHEMBL6588689 | 0.89 | CTSK (0.38) | CTSLCTSKCTSS | |
| SCHEMBL6590302 | 0.88 | CTSK (0.34) | CTSLCTSKCTSS | |
| SCHEMBL6589183 | 0.88 | CTSK (0.34) | CTSLCTSKCTSS | |
| SCHEMBL6592875 | 0.88 | CTSK (0.37) | CTSLCTSKCTSS | |
| SCHEMBL6591389 | 0.87 | CTSL (0.33) | CTSLCTSKCTSS | |
| SCHEMBL6476297 | 0.87 | CTSL (0.48) | CTSLCTSKCTSS | |
| SCHEMBL6591740 | 0.86 | CTSK (0.36) | CTSLCTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178986-B1 | FURANONE DERIVATIVES AS INHIBITORS OF CATHEPSIN S | MEDIVIR UK LTD (GB) | 2004-02-25 | — | — | EP | claimed |