Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | TUBB4A | P04350 | 8/20 | 0.45 |
| ▸ | TUBB | P07437 | 8/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 8/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 8/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 8/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 8/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 8/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 8/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 8/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 8/20 | 0.45 |
| ▸ | TUBA1A | Q71U36 | 8/20 | 0.45 |
| ▸ | TUBA1C | Q9BQE3 | 8/20 | 0.45 |
| ▸ | TUBB6 | Q9BUF5 | 8/20 | 0.45 |
| ▸ | TUBB2B | Q9BVA1 | 8/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 8/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6589679 | 1.00 | KDM4E (0.63) | KDM4EALDH1A1LMNAMAPTTUBB4A | |
| SCHEMBL6665608 | 0.92 | KDM4E (0.55) | KDM4EALDH1A1LMNAMAPTTUBB4A | |
| SCHEMBL6665807 | 0.92 | KDM4E (0.55) | KDM4EALDH1A1LMNAMAPTTUBB4A | |
| SCHEMBL6597415 | 0.81 | PDE3B (0.44) | KDM4EALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL6597409 | 0.81 | PDE3B (0.44) | KDM4EALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL6664659 | 0.78 | MEN1 (0.45) | KDM4EALDH1A1LMNAMAPTTUBB1 | |
| SCHEMBL6595261 | 0.78 | KDM4E (1.00) | KDM4EALDH1A1LMNAMAPTTUBB4A | |
| SCHEMBL6595258 | 0.78 | KDM4E (1.00) | KDM4EALDH1A1LMNAMAPTTUBB4A | |
| SCHEMBL6593056 | 0.75 | APP (0.50) | KDM4EALDH1A1MAPTKMT2ACYP1A2 | |
| SCHEMBL6593053 | 0.75 | APP (0.50) | KDM4EALDH1A1MAPTKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389461-A1 | Pyrimidones with antiviral properties | Axxima Pharmaceuticals Aktiengesellschaft (DE) | 2004-02-18 | — | — | EP | claimed |
| WO-2004016271-A1 | PYRIMIDONES AS ANTIVIRAL AGENTS | AXXIMA PHARMACEUTICALS AG (DE) | 2004-02-26 | — | — | WO | disclosed |
| EP-1389461-A1 | Pyrimidones with antiviral properties | Axxima Pharmaceuticals Aktiengesellschaft (DE) | 2004-02-18 | — | — | EP | disclosed |