Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.38 |
| ▸ | TUBB | P07437 | 3/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6665807 | 1.00 | KDM4E (0.55) | KDM4EALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL6589679 | 0.92 | KDM4E (0.63) | KDM4EALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL6589681 | 0.92 | KDM4E (0.63) | KDM4EALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL6664659 | 0.85 | MEN1 (0.45) | KDM4EALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL6597177 | 0.80 | KDM4E (0.85) | KDM4EALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL6597180 | 0.80 | KDM4E (0.85) | KDM4EALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL6664825 | 0.77 | TNF (0.39) | KDM4EALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL6661728 | 0.77 | TNF (0.39) | KDM4EALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL6597415 | 0.76 | PDE3B (0.44) | KDM4EALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL6597409 | 0.76 | PDE3B (0.44) | KDM4EALDH1A1MAPTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004016271-A1 | PYRIMIDONES AS ANTIVIRAL AGENTS | AXXIMA PHARMACEUTICALS AG (DE) | 2004-02-26 | — | — | WO | claimed |
| WO-2004016271-A1 | PYRIMIDONES AS ANTIVIRAL AGENTS | AXXIMA PHARMACEUTICALS AG (DE) | 2004-02-26 | — | — | WO | disclosed |