Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6590000 | 1.00 | LTA4H (0.44) | LTA4HPOLBKMT2AL3MBTL1KDM4E | |
| SCHEMBL6589684 | 1.00 | LTA4H (0.44) | LTA4HPOLBKMT2AL3MBTL1KDM4E | |
| SCHEMBL6591854 | 0.85 | LTA4H (0.45) | LTA4HPOLBKMT2AL3MBTL1KDM4E | |
| SCHEMBL6588677 | 0.85 | LTA4H (0.45) | LTA4HPOLBKMT2AL3MBTL1KDM4E | |
| SCHEMBL6588681 | 0.85 | LTA4H (0.45) | LTA4HPOLBKMT2AL3MBTL1KDM4E | |
| SCHEMBL6588673 | 0.84 | LTA4H (0.44) | LTA4HPOLBKMT2ASIGMAR1 | |
| SCHEMBL6588665 | 0.84 | LTA4H (0.44) | LTA4HPOLBKMT2ASIGMAR1 | |
| SCHEMBL6590734 | 0.84 | LTA4H (0.44) | LTA4HPOLBKMT2ASIGMAR1 | |
| SCHEMBL6588441 | 0.80 | OPRK1 (0.36) | POLBKMT2AL3MBTL1KDM4ENPSR1 | |
| SCHEMBL6588438 | 0.80 | OPRK1 (0.36) | POLBKMT2AL3MBTL1KDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934308-B1 | 3-PYRIDYLOXYMETHYL HETEROCYCLIC ETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LAB (US) | 2004-08-11 | — | — | EP | claimed |