Sugi Predict

Sugi Predict / Compounds / SCHEMBL6589722

SCHEMBL6589722

SCHEMBL6589722

Cc1cc(C2=CCN(S(=O)(=O)CC(=O)NO)CC2)ccc1-c1ccncc1

nearest known ligand 0.81

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ MMP3 P08254 13/20 0.81
▸ MMP2 P08253 12/20 0.81
▸ WNT3A P56704 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ CCNT1 O60563 5/20 0.38
▸ CDK9 P50750 5/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6586215 0.90 MMP3 (1.00) MMP3MMP2L3MBTL1
SCHEMBL6584819 0.89 MMP3 (0.80) MMP3MMP2L3MBTL1
SCHEMBL6584461 0.89 MMP2 (0.65) MMP3MMP2L3MBTL1CCNT1CDK9
SCHEMBL6588213 0.85 MMP3 (0.76) MMP3MMP2WNT3AL3MBTL1CCNT1
SCHEMBL6585982 0.85 MMP3 (0.86) MMP3MMP2L3MBTL1
SCHEMBL6587727 0.84 MMP3 (0.76) MMP3MMP2L3MBTL1
SCHEMBL6590023 0.83 MMP2 (0.77) MMP3MMP2CCNT1CDK9
SCHEMBL6585994 0.83 MMP3 (0.74) MMP3MMP2L3MBTL1
SCHEMBL6584456 0.83 MMP3 (1.00) MMP3MMP2L3MBTL1
SCHEMBL6583128 0.83 MMP2 (0.73) MMP3MMP2CCNT1CDK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1036062-B1 HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE (MMP) INHIBITORS PFIZER LTD (GB) 2004-01-02 — — EP disclosed
US-6495568-B1 TREATMENT OF TISSUE ULCERATION, WOUND REPAIR AND SKIN DISEASES WARNER-LAMBERT COMPANY 2002-12-17 — — US disclosed