Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | GSK3A | P49840 | 2/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.41 |
| ▸ | MARK3 | P27448 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | ITK | Q08881 | 1/20 | 0.41 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.41 |
| ▸ | MARK2 | Q7KZI7 | 1/20 | 0.41 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.41 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6810278 | 0.86 | PIM1 (0.54) | PIM1GSK3ADYRK1APIM3AURKB | |
| SCHEMBL6799854 | 0.83 | PKN1 (0.47) | PIM1GSK3ADYRK1APIM3AURKB | |
| SCHEMBL6804009 | 0.83 | PIM1 (0.44) | PIM1GSK3ADYRK1APIM3AURKB | |
| SCHEMBL6586959 | 0.83 | KDM4E (0.56) | PARP1KDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL6592104 | 0.81 | PIM1 (0.44) | PIM1GSK3ADYRK1APIM3AURKB | |
| SCHEMBL6587773 | 0.80 | PARP1 (0.46) | PARP1KDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL6586851 | 0.79 | PIM1 (0.48) | PIM1GSK3ADYRK1APIM3AURKB | |
| SCHEMBL6585045 | 0.78 | PIM1 (0.48) | PIM1GSK3ADYRK1APIM3AURKB | |
| SCHEMBL6810283 | 0.76 | PARP1 (0.42) | PIM1GSK3ADYRK1APIM3AURKB | |
| SCHEMBL7764199 | 0.75 | PIM1 (0.55) | PIM1GSK3ADYRK1APIM3AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177178-B1 | HETEROCYCLICALLY SUBSTITUTED BENZIMIDAZOLES, THE PRODUCTION AND APPLICATION THEREOF | ABBOTT GMBH & CO KG (DE) | 2004-12-29 | — | — | EP | disclosed |