Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9704586 | 0.79 | CREBBP (0.43) | ARPGR | |
| SCHEMBL14401750 | 0.76 | AR (0.44) | ARPGR | |
| SCHEMBL12156816 | 0.76 | AR (0.44) | ARPGR | |
| SCHEMBL11724231 | 0.73 | ACHE (0.47) | ARPGR | |
| SCHEMBL9704675 | 0.71 | CES1 (0.39) | ARPGR | |
| SCHEMBL11715697 | 0.69 | KDM4E (0.50) | — | |
| SCHEMBL22868112 | 0.68 | ACHE (0.46) | — | |
| SCHEMBL20288981 | 0.67 | PBRM1 (0.51) | AR | |
| SCHEMBL19203473 | 0.67 | CREBBP (0.49) | ARPGR | |
| SCHEMBL222096 | 0.66 | PBRM1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1114033-B1 | 4-CARBOXYAMINO-2-METHYL-1,2,3,4-TETRAHYDROQUINOLINES AS CETP INHIBITORS | PFIZER PROD INC (US) | 2004-09-29 | — | — | EP | disclosed |
| US-6395751-B1 | SYNERGISTIC MIXTURE; ANTICHOLESTEROL AGENTS | PFIZER INC. | 2002-05-28 | — | — | US | disclosed |
| EP-1114033-A1 | 4-CARBOXYAMINO-2-METHYL-1,2,3,4-TETRAHYDROQUINOLINES AS CETP INHIBITORS | Pfizer Products Inc. (US) | 2001-07-11 | — | — | EP | disclosed |
| US-6147090-A | CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS USED TO TREAT DISEASES WHICH ARE EXACERBATED BY LOW LEVELS OF HDL CHOLESTEROL AND/OR HIGH LEVELS OF LDL-CHOLESTEROL AND TRIGLYCERIDES, SUCH AS ATHEROSCLEROSIS AND CARDIOVASCULAR | PFIZER INC. (US) | 2000-11-14 | — | — | US | disclosed |
| WO-2000017166-A1 | 4-CARBOXYAMINO-2-METHYL-1,2,3,4-TETRAHYDROQUINOLINES AS CETP INHIBITORS | PFIZER PRODUCTS INC. (US) | 2000-03-30 | — | — | WO | disclosed |