Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 12/20 | 0.47 |
| ▸ | MMP3 | P08254 | 12/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | QDPR | P09417 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6585837 | 0.90 | MMP2 (0.50) | MMP2MMP3L3MBTL1LMNATHRB | |
| SCHEMBL6437646 | 0.87 | MMP2 (0.48) | MMP2MMP3L3MBTL1LMNATHRB | |
| SCHEMBL6437476 | 0.80 | MMP2 (0.49) | MMP2MMP3L3MBTL1LMNATHRB | |
| SCHEMBL6590177 | 0.78 | MMP2 (0.53) | MMP2MMP3L3MBTL1KMT2A | |
| SCHEMBL6440525 | 0.76 | MMP2 (0.59) | MMP2MMP3L3MBTL1LMNATHRB | |
| SCHEMBL6965353 | 0.72 | MMP2 (0.46) | MMP2MMP3L3MBTL1LMNATHRB | |
| SCHEMBL31222903 | 0.72 | NAMPT (0.54) | QDPR | |
| SCHEMBL6587473 | 0.72 | MMP2 (0.58) | MMP2MMP3L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL6433272 | 0.71 | MMP2 (0.44) | MMP2MMP3L3MBTL1PKM | |
| SCHEMBL6585480 | 0.70 | MMP2 (0.61) | MMP2MMP3L3MBTL1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036062-B1 | HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE (MMP) INHIBITORS | PFIZER LTD (GB) | 2004-01-02 | — | — | EP | disclosed |
| US-6495568-B1 | TREATMENT OF TISSUE ULCERATION, WOUND REPAIR AND SKIN DISEASES | WARNER-LAMBERT COMPANY | 2002-12-17 | — | — | US | disclosed |