Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 14/20 | 0.46 |
| ▸ | MMP3 | P08254 | 13/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 2/20 | 0.36 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6433272 | 0.90 | MMP2 (0.44) | MMP2MMP3L3MBTL1ABL1RIN1 | |
| SCHEMBL6963708 | 0.87 | MMP2 (0.42) | MMP2MMP3L3MBTL1MMP14ADAMTS5 | |
| SCHEMBL6583989 | 0.87 | MMP2 (0.60) | MMP2MMP3L3MBTL1MMP14ADAMTS5 | |
| SCHEMBL6584500 | 0.83 | MMP2 (0.53) | MMP2MMP3L3MBTL1MMP14ADAMTS5 | |
| SCHEMBL6584396 | 0.81 | MMP2 (0.54) | MMP2MMP3ADAM10ALDH1A1 | |
| SCHEMBL6584555 | 0.81 | MMP2 (0.63) | MMP2MMP3L3MBTL1MMP14MMP9 | |
| SCHEMBL6584009 | 0.80 | MMP2 (0.64) | MMP2MMP3L3MBTL1MMP14MMP9 | |
| SCHEMBL6586997 | 0.80 | MMP2 (0.59) | MMP2MMP3L3MBTL1MMP9ADAM10 | |
| SCHEMBL6588431 | 0.79 | MMP2 (0.66) | MMP2MMP3L3MBTL1MMP9ADAM10 | |
| SCHEMBL6586078 | 0.78 | MMP2 (0.64) | MMP2MMP3L3MBTL1MMP14ADAMTS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181017-B1 | METALLOPROTEASE INHIBITORS | PFIZER LTD (GB) | 2003-04-16 | — | — | EP | claimed |