Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6590116 | 1.00 | CYP2C9 (0.57) | CYP2C9SMN1; SMN2GAAPTPN1ALDH1A1 | |
| SCHEMBL24310874 | 0.86 | CYP2C9 (0.51) | CYP2C9SMN1; SMN2GAAPTPN1ALDH1A1 | |
| Acetic Acid SCHEMBL27603523 | 0.84 | SMN1; SMN2 (0.56) | CYP2C9SMN1; SMN2GAAPTPN1ALDH1A1 | |
| SCHEMBL28050188 | 0.83 | ALOX12 (0.60) | CYP2C9SMN1; SMN2GAAPTPN1ALDH1A1 | |
| SCHEMBL1403667 | 0.81 | ALOX12 (0.58) | CYP2C9SMN1; SMN2GAAPTPN1ALDH1A1 | |
| SCHEMBL3222641 | 0.80 | ALDH1A1 (0.54) | CYP2C9SMN1; SMN2GAAPTPN1ALDH1A1 | |
| SCHEMBL215283 | 0.80 | PPID (0.56) | CYP2C9SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL215282 | 0.80 | PPID (0.56) | CYP2C9SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL97001 | 0.79 | KMT2A (0.68) | CYP2C9SMN1; SMN2GAAPTPN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6369465 | 0.79 | ALOX12 (0.56) | CYP2C9SMN1; SMN2GAAPTPN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1030841-B1 | PROCESS FOR THE PREPARATION OF 1,4-DIHYDROPYRIDINES AND COMPOUNDS USED IN THIS PROCESS | GEA FARMACEUTISK FABRIK AS (DK) | 2004-09-22 | — | — | EP | disclosed |
| EP-1030841-A1 | PROCESS FOR THE PREPARATION OF 1,4-DIHYDROPYRIDINES AND COMPOUNDS USED IN THIS PROCESS | A/S GEA Farmaceutisk Fabrik (DK) | 2000-08-30 | — | — | EP | disclosed |
| WO-1999025689-A1 | PROCESS FOR THE PREPARATION OF ACETAL DERIVATIVES OF 1,4-DIHYDROPYRIDINES | A/S GEA FARMACEUTISK FABRIK (DK) | 1999-05-27 | — | — | WO | disclosed |
| WO-1999025688-A1 | PROCESS FOR THE PREPARATION OF 1,4-DIHYDROPYRIDINES AND COMPOUNDS USED IN THIS PROCESS | A/S GEA FARMACEUTISK FABRIK (DK) | 1999-05-27 | — | — | WO | disclosed |