Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 8/20 | 0.63 |
| ▸ | MMP3 | P08254 | 8/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | USP5 | P45974 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6587473 | 0.88 | MMP2 (0.58) | MMP2MMP3ALDH1A1PKML3MBTL1 | |
| SCHEMBL6586274 | 0.86 | MMP2 (0.55) | MMP2MMP3KDM4EMMP14 | |
| SCHEMBL6584729 | 0.85 | MMP2 (0.63) | MMP2MMP3ALDH1A1PKML3MBTL1 | |
| SCHEMBL6587433 | 0.78 | MMP3 (1.00) | MMP2MMP3ALDH1A1PKMKDM4E | |
| SCHEMBL6590247 | 0.77 | MMP2 (0.58) | MMP2MMP3ALDH1A1PKML3MBTL1 | |
| SCHEMBL6586191 | 0.77 | MMP2 (0.76) | MMP2MMP3MMP14 | |
| SCHEMBL6590943 | 0.77 | MMP2 (0.54) | MMP2MMP3MMP14 | |
| SCHEMBL6585805 | 0.76 | MMP2 (0.57) | MMP2MMP3ALDH1A1PKML3MBTL1 | |
| SCHEMBL19989648 | 0.75 | SLC6A2 (0.54) | MMP2MMP3KDM4E | |
| SCHEMBL6587154 | 0.75 | MMP2 (0.52) | MMP2MMP3ALDH1A1PKML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036062-B1 | HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE (MMP) INHIBITORS | PFIZER LTD (GB) | 2004-01-02 | — | — | EP | disclosed |
| US-6495568-B1 | TREATMENT OF TISSUE ULCERATION, WOUND REPAIR AND SKIN DISEASES | WARNER-LAMBERT COMPANY | 2002-12-17 | — | — | US | disclosed |