Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 20/20 | 0.51 |
| ▸ | CTSL | P07711 | 19/20 | 0.51 |
| ▸ | CTSS | P25774 | 19/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6482599 | 1.00 | CTSK (0.51) | CTSKCTSLCTSS | |
| SCHEMBL6475726 | 0.92 | CTSK (0.61) | CTSKCTSLCTSS | |
| SCHEMBL6476330 | 0.90 | CTSL (0.50) | CTSKCTSLCTSS | |
| SCHEMBL6475015 | 0.90 | CTSK (0.54) | CTSKCTSLCTSS | |
| SCHEMBL6476624 | 0.90 | CTSK (0.51) | CTSKCTSLCTSS | |
| SCHEMBL7468741 | 0.89 | CTSL (0.64) | CTSKCTSLCTSS | |
| SCHEMBL6475386 | 0.89 | CTSL (0.64) | CTSKCTSLCTSS | |
| SCHEMBL6475188 | 0.88 | CTSL (0.49) | CTSKCTSLCTSS | |
| SCHEMBL6488834 | 0.88 | CTSL (0.69) | CTSKCTSLCTSS | |
| SCHEMBL6483197 | 0.88 | CTSK (0.50) | CTSKCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178986-B1 | FURANONE DERIVATIVES AS INHIBITORS OF CATHEPSIN S | MEDIVIR UK LTD (GB) | 2004-02-25 | — | — | EP | disclosed |