Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 13/20 | 0.46 |
| ▸ | CTSS | P25774 | 11/20 | 0.46 |
| ▸ | CTSL | P07711 | 7/20 | 0.46 |
| ▸ | CTSB | P07858 | 4/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6593114 | 0.93 | CTSK (0.47) | CTSKCTSSCTSLCTSBSCN9A | |
| SCHEMBL6587778 | 0.91 | CTSL (0.56) | CTSKCTSSCTSL | |
| SCHEMBL6588768 | 0.89 | CTSL (0.52) | CTSKCTSSCTSL | |
| SCHEMBL6590851 | 0.89 | CTSK (0.48) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6588785 | 0.88 | CTSL (0.58) | CTSKCTSSCTSL | |
| SCHEMBL6592446 | 0.88 | CTSK (0.37) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6476150 | 0.88 | CTSL (0.61) | CTSKCTSSCTSL | |
| SCHEMBL6591740 | 0.88 | CTSK (0.36) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6594735 | 0.87 | CTSK (0.45) | CTSKCTSSCTSLCTSBSCN9A | |
| SCHEMBL6590008 | 0.87 | CTSK (0.46) | CTSKCTSSCTSLCTSBSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178986-B1 | FURANONE DERIVATIVES AS INHIBITORS OF CATHEPSIN S | MEDIVIR UK LTD (GB) | 2004-02-25 | — | — | EP | claimed |