⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6592821 | 1.00 | — | — | |
| SCHEMBL645887 | 0.78 | ALDH1A1 (0.33) | — | |
| Serine SCHEMBL1253823 | 0.77 | SLC1A1 (0.41) | — | |
| Serine SCHEMBL442652 | 0.77 | SLC1A1 (0.41) | — | |
| SCHEMBL7416554 | 0.72 | SLC1A1 (0.33) | — | |
| SCHEMBL6550328 | 0.72 | RNPEP (0.36) | — | |
| SCHEMBL3267512 | 0.71 | — | — | |
| Serine SCHEMBL3185132 | 0.70 | SLC1A1 (0.52) | — | |
| SCHEMBL29498253 | 0.70 | — | — | |
| SCHEMBL1633647 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1413580-A1 | Furanone derivatives as inhibitors of Cathepsin S | Medivir UK Ltd (GB) | 2004-04-28 | — | — | EP | disclosed |
| EP-1178986-B1 | FURANONE DERIVATIVES AS INHIBITORS OF CATHEPSIN S | MEDIVIR UK LTD (GB) | 2004-02-25 | — | — | EP | disclosed |
| US-20030203900-A1 | Cysteine protease inhibitors | MEDIVIR UK LTD (GB) | 2003-10-30 | — | — | US | disclosed |