Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4832565 | 0.87 | — | — | |
| SCHEMBL6591163 | 0.80 | KMT2A (0.33) | KMT2A | |
| SCHEMBL6587495 | 0.78 | TRPM8 (0.35) | KMT2A | |
| SCHEMBL6593956 | 0.76 | SLC6A2 (0.34) | — | |
| SCHEMBL4768444 | 0.76 | — | — | |
| SCHEMBL6589463 | 0.75 | — | — | |
| SCHEMBL6591070 | 0.74 | — | — | |
| SCHEMBL4761934 | 0.74 | HPGD (0.36) | KMT2ANPC1RAB9A | |
| SCHEMBL4767101 | 0.72 | CTSD (0.37) | KMT2A | |
| SCHEMBL4763307 | 0.71 | PSEN1 (0.32) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307204-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2004-06-02 | — | — | EP | disclosed |
| EP-1307204-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2003-05-07 | — | — | EP | disclosed |
| WO-2001095911-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-12-20 | — | — | WO | disclosed |