Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6591623 | 1.00 | KDM4E (0.55) | KDM4EALDH1A1RXRAMAPTMEN1 | |
| SCHEMBL6668285 | 0.89 | MEN1 (0.52) | KDM4EALDH1A1RXRAMAPTMEN1 | |
| SCHEMBL16211020 | 0.88 | PSD (0.55) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL16211019 | 0.88 | PSD (0.55) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL13479595 | 0.83 | MEN1 (0.53) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6664624 | 0.81 | PSD (0.52) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6662372 | 0.81 | MEN1 (0.49) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6664657 | 0.80 | MEN1 (0.50) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6684366 | 0.79 | KMT2A (0.46) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6663749 | 0.77 | MAPT (0.48) | KDM4EALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389461-A1 | Pyrimidones with antiviral properties | Axxima Pharmaceuticals Aktiengesellschaft (DE) | 2004-02-18 | — | — | EP | claimed |
| EP-1389461-A1 | Pyrimidones with antiviral properties | Axxima Pharmaceuticals Aktiengesellschaft (DE) | 2004-02-18 | — | — | EP | disclosed |