Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | MEN1 | O00255 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | POLB | P06746 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.45 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.45 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.45 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.43 |
| ▸ | PHGDH | O43175 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13479595 | 0.83 | MEN1 (0.53) | MAPTMEN1KMT2APOLBLMNA | |
| SCHEMBL6662372 | 0.80 | MEN1 (0.49) | MAPTMEN1KMT2APOLBLMNA | |
| SCHEMBL6664624 | 0.77 | PSD (0.52) | MAPTMEN1KMT2APOLBLMNA | |
| SCHEMBL6668285 | 0.77 | MEN1 (0.52) | MAPTMEN1KMT2APOLBLMNA | |
| SCHEMBL6591623 | 0.77 | KDM4E (0.55) | MAPTMEN1KMT2APOLBLMNA | |
| SCHEMBL6591626 | 0.77 | KDM4E (0.55) | MAPTMEN1KMT2APOLBLMNA | |
| SCHEMBL16211019 | 0.76 | PSD (0.55) | MAPTMEN1KMT2APOLBLMNA | |
| SCHEMBL16211020 | 0.76 | PSD (0.55) | MAPTMEN1KMT2APOLBLMNA | |
| SCHEMBL6664657 | 0.74 | MEN1 (0.50) | MAPTMEN1KMT2APOLBLMNA | |
| SCHEMBL6662761 | 0.73 | MEN1 (0.70) | MAPTMEN1KMT2APOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004016271-A1 | PYRIMIDONES AS ANTIVIRAL AGENTS | AXXIMA PHARMACEUTICALS AG (DE) | 2004-02-26 | — | — | WO | disclosed |