Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL7628894 | 0.98 | IDO1 (0.38) | GAAL3MBTL1IDO1HIF1AALDH1A1 | |
| Iodide SCHEMBL7633294 | 0.98 | IDO1 (0.38) | GAAL3MBTL1IDO1HIF1AALDH1A1 | |
| Iodide SCHEMBL7629435 | 0.98 | IDO1 (0.38) | GAAL3MBTL1IDO1HIF1AALDH1A1 | |
| SCHEMBL31321441 | 0.97 | GAA (0.38) | GAAL3MBTL1IDO1HIF1AALDH1A1 | |
| Bromide SCHEMBL2447458 | 0.95 | GAA (0.36) | GAAL3MBTL1IDO1HIF1AALDH1A1 | |
| SCHEMBL29515524 | 0.95 | IDO1 (0.39) | GAAL3MBTL1IDO1HIF1AALDH1A1 | |
| Hydrochloric Acid SCHEMBL6633309 | 0.95 | GAA (0.36) | GAAL3MBTL1IDO1HIF1AALDH1A1 | |
| Water SCHEMBL6634553 | 0.95 | GAA (0.36) | GAAL3MBTL1IDO1HIF1AALDH1A1 | |
| Iodide SCHEMBL7626801 | 0.95 | HIF1A (0.35) | GAAL3MBTL1HIF1ACYP2D6 | |
| Hydrochloric Acid SCHEMBL7629171 | 0.93 | IDO1 (0.38) | GAAL3MBTL1IDO1HIF1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0329021-B1 | Preparation of advanced epoxy resins and dihydric phenols in the presence of phosphonium compounds | DOW CHEMICAL CO (US) | 1994-01-26 | — | — | EP | claimed |
| EP-0329021-A2 | Preparation of advanced epoxy resins and dihydric phenols in the presence of phosphonium compounds | THE DOW CHEMICAL COMPANY (US) | 1989-08-23 | — | — | EP | claimed |
| US-4808692-A | Preparation of advanced epoxy resins from epoxy resins and dihydric phenols in the presence of phosphonium compounds | THE DOW CHEMICAL COMPANY (US) | 1989-02-28 | — | — | US | claimed |
| CN-103553873-A | Cyclopentylene cyclohexyl compound as well as preparation method and application thereof | BEIJING BAYI SPACE LCD MATERIALS TECHNOLOGY CO LTD | 2014-02-05 | — | — | CN | disclosed |
| EP-0823423-B1 | 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-06-16 | — | — | EP | disclosed |
| EP-0780452-B1 | Aqueous paint | TOYO SEIKAN KAISHA LTD (JP) | 2002-03-06 | — | — | EP | disclosed |
| US-5763507-A | EPOXY ACRYLATE RESIN | TOYO SEIKAN KAISHA, LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| US-5750540-A | SIDE EFFECT REDUCTION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0823423-A1 | 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-02-11 | — | — | EP | disclosed |
| EP-0780452-A2 | Aqueous paint | TOYO SEIKAN KAISHA LIMITED (JP) | 1997-06-25 | — | — | EP | disclosed |
| US-5310854-A | Solvent, coatings for beverage cans | THE DOW CHEMICAL COMPANY (US) | 1994-05-10 | — | — | US | disclosed |
| EP-0329021-B1 | Preparation of advanced epoxy resins and dihydric phenols in the presence of phosphonium compounds | DOW CHEMICAL CO (US) | 1994-01-26 | — | — | EP | disclosed |
| US-5206312-A | Polysiloxanes hydrosilated with unsaturated aromatic alcohols and siloxy-containing compounds having hydroxy groups to advance polyepoxides and epoxy resins; electronics; coatings; composites | THE DOW CHEMICAL COMPANY (US) | 1993-04-27 | — | — | US | disclosed |
| EP-0329021-A2 | Preparation of advanced epoxy resins and dihydric phenols in the presence of phosphonium compounds | THE DOW CHEMICAL COMPANY (US) | 1989-08-23 | — | — | EP | disclosed |
| US-4808692-A | Preparation of advanced epoxy resins from epoxy resins and dihydric phenols in the presence of phosphonium compounds | THE DOW CHEMICAL COMPANY (US) | 1989-02-28 | — | — | US | disclosed |