Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL6591776 | 0.95 | GAA (0.36) | HIF1ACYP2D6GAAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL7631802 | 0.95 | HIF1A (0.35) | HIF1ASLC18A2CYP1A2CYP2D6GAA | |
| Bromide SCHEMBL3389414 | 0.95 | HIF1A (0.35) | HIF1ASLC18A2CYP1A2CYP2D6GAA | |
| Iodide SCHEMBL7628894 | 0.93 | IDO1 (0.38) | HIF1AGAAL3MBTL1 | |
| Iodide SCHEMBL7629435 | 0.93 | IDO1 (0.38) | HIF1AGAAL3MBTL1 | |
| Iodide SCHEMBL7633294 | 0.93 | IDO1 (0.38) | HIF1AGAAL3MBTL1 | |
| Iodide SCHEMBL7634472 | 0.92 | HIF1A (0.36) | HIF1A | |
| SCHEMBL31321441 | 0.92 | GAA (0.38) | HIF1ACYP2D6GAAL3MBTL1 | |
| Water SCHEMBL6634553 | 0.90 | GAA (0.36) | HIF1ACYP2D6GAAL3MBTL1 | |
| Bromide SCHEMBL2447458 | 0.90 | GAA (0.36) | HIF1ACYP2D6GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780452-B1 | Aqueous paint | TOYO SEIKAN KAISHA LTD (JP) | 2002-03-06 | — | — | EP | disclosed |
| US-5763507-A | EPOXY ACRYLATE RESIN | TOYO SEIKAN KAISHA, LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| EP-0780452-A2 | Aqueous paint | TOYO SEIKAN KAISHA LIMITED (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0414160-B1 | Process for preparing advanced epoxy resins | DOW CHEMICAL CO (US) | 1996-09-11 | — | — | EP | disclosed |
| US-5310854-A | Solvent, coatings for beverage cans | THE DOW CHEMICAL COMPANY (US) | 1994-05-10 | — | — | US | disclosed |
| EP-0329021-B1 | Preparation of advanced epoxy resins and dihydric phenols in the presence of phosphonium compounds | DOW CHEMICAL CO (US) | 1994-01-26 | — | — | EP | disclosed |
| US-5206312-A | Polysiloxanes hydrosilated with unsaturated aromatic alcohols and siloxy-containing compounds having hydroxy groups to advance polyepoxides and epoxy resins; electronics; coatings; composites | THE DOW CHEMICAL COMPANY (US) | 1993-04-27 | — | — | US | disclosed |
| EP-0414160-A2 | Process for preparing advanced epoxy resins | THE DOW CHEMICAL COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |
| EP-0329021-A2 | Preparation of advanced epoxy resins and dihydric phenols in the presence of phosphonium compounds | THE DOW CHEMICAL COMPANY (US) | 1989-08-23 | — | — | EP | disclosed |
| US-4808692-A | Preparation of advanced epoxy resins from epoxy resins and dihydric phenols in the presence of phosphonium compounds | THE DOW CHEMICAL COMPANY (US) | 1989-02-28 | — | — | US | disclosed |