Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.38 |
| ▸ | CNR2 | P34972 | 6/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31317634 | 0.90 | CNR1 (0.40) | CNR1CNR2TRPA1TRPV1ALDH1A1 | |
| SCHEMBL9870399 | 0.83 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2MMP1MMP2MMP3 | |
| SCHEMBL28293734 | 0.79 | MMP1 (0.48) | ALDH1A1SMN1; SMN2MMP1MMP2MMP3 | |
| SCHEMBL320068 | 0.79 | — | — | |
| SCHEMBL8368739 | 0.78 | CNR1 (0.37) | CNR1CNR2TRPA1TRPV1ALDH1A1 | |
| SCHEMBL622102 | 0.77 | SMN1; SMN2 (0.34) | CNR2ALDH1A1SMN1; SMN2MMP1MMP2 | |
| SCHEMBL6286877 | 0.77 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2MMP1MMP2MMP3 | |
| SCHEMBL124496 | 0.76 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2MMP1MMP2MMP3 | |
| SCHEMBL966577 | 0.76 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2MMP1MMP2MMP3 | |
| SCHEMBL6287596 | 0.76 | SMN1; SMN2 (0.37) | ALDH1A1SMN1; SMN2MMP1MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1040108-B1 | ORTHO-ANTHRANILAMIDE DERIVATIVES AS ANTI-COAGULANTS | SCHERING AG (DE) | 2004-02-25 | — | — | EP | disclosed |
| US-6498185-B1 | ENZYME FACTOR XA INHIBITORS | BERLEX LABORATORIES, INC. | 2002-12-24 | — | — | US | disclosed |
| US-6380221-B1 | FOR THERAPY OF DISEASE-STATES CHARACTERIZED BY THROMBOTIC ACTIVITY | BERLEX LABORATORIES, INC. | 2002-04-30 | — | — | US | disclosed |
| US-6140351-A | FOR TREATING THROMBOSIS | BERLEX LABORATORIES, INC. (US) | 2000-10-31 | — | — | US | disclosed |