Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 2/20 | 0.58 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.58 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.58 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.58 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.58 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.58 |
| ▸ | FRK | P42685 | 1/20 | 0.58 |
| ▸ | GSK3B | P49841 | 1/20 | 0.58 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.58 |
| ▸ | MAPK13 | O15264 | 8/20 | 0.53 |
| ▸ | MAPK12 | P53778 | 8/20 | 0.53 |
| ▸ | MAPK11 | Q15759 | 8/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.45 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.44 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6591428 | 0.99 | MAP4K4 (0.56) | MAP4K4MAPK9CSNK1A1CSNK1DMAP4K5 | |
| SCHEMBL6844081 | 0.89 | MAPK13 (0.56) | MAP4K4MAPK9CSNK1A1CSNK1DMAP4K5 | |
| SCHEMBL6844345 | 0.88 | MAP4K4 (0.54) | MAP4K4MAPK9CSNK1A1CSNK1DMAP4K5 | |
| SCHEMBL6847084 | 0.88 | MAPK13 (0.55) | MAP4K4MAPK9CSNK1A1CSNK1DMAP4K5 | |
| SCHEMBL6598279 | 0.87 | MAPK13 (0.62) | MAP4K4MAPK9CSNK1A1CSNK1DMAP4K5 | |
| SCHEMBL6844358 | 0.87 | MAP4K4 (0.53) | MAP4K4MAPK9CSNK1A1CSNK1DMAP4K5 | |
| SCHEMBL6590919 | 0.86 | MAPK13 (0.61) | MAP4K4MAPK9CSNK1A1CSNK1DMAP4K5 | |
| SCHEMBL6844335 | 0.85 | MAPK13 (0.71) | MAP4K4MAPK9CSNK1A1CSNK1DMAP4K5 | |
| SCHEMBL6839498 | 0.84 | MAPK13 (0.60) | MAP4K4MAPK9CSNK1A1CSNK1DMAP4K5 | |
| SCHEMBL6847077 | 0.84 | MAPK13 (0.70) | MAP4K4MAPK9CSNK1A1CSNK1DMAP4K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1649846-A | Compounds of the family of 3-alkyl-(4,5-diphenyl-imidazol-1-yl) and their use as soothing agents | OREAL (FR) | 2005-08-03 | — | — | CN | claimed |
| US-20040162328-A1 | Compounds of the family of 3-alkyl-(4,5-diphenyl-imidazol-1-yl) and their use as soothing agents | L'OREAL (FR) | 2004-08-19 | — | — | US | claimed |
| EP-1385828-A1 | COMPOUNDS OF THE FAMILY OF 3-ALKYL-(4,5 DIPHENY-IMIDAZOL-1-YL) AND THEIR USE AS SOOTHING AGENTS | L'OREAL (FR) | 2004-02-04 | — | — | EP | claimed |
| WO-2002085864-A1 | COMPOUNDS OF THE FAMILY OF 3-ALKYL-(4,5 DIPHENY-IMIDAZOL-1-YL) AND THEIR USE AS SOOTHING AGENTS | L'OREAL (FR) | 2002-10-31 | — | — | WO | claimed |
| CN-1649846-A | Compounds of the family of 3-alkyl-(4,5-diphenyl-imidazol-1-yl) and their use as soothing agents | OREAL (FR) | 2005-08-03 | — | — | CN | disclosed |
| US-20040162328-A1 | Compounds of the family of 3-alkyl-(4,5-diphenyl-imidazol-1-yl) and their use as soothing agents | L'OREAL (FR) | 2004-08-19 | — | — | US | disclosed |
| EP-1385828-A1 | COMPOUNDS OF THE FAMILY OF 3-ALKYL-(4,5 DIPHENY-IMIDAZOL-1-YL) AND THEIR USE AS SOOTHING AGENTS | L'OREAL (FR) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002085864-A1 | COMPOUNDS OF THE FAMILY OF 3-ALKYL-(4,5 DIPHENY-IMIDAZOL-1-YL) AND THEIR USE AS SOOTHING AGENTS | L'OREAL (FR) | 2002-10-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040162328-A1 | Compounds of the family of 3-alkyl-(4,5-diphenyl-imidazol-1-yl) and their use as soothing agents | TRPV1, TRPA1, TRPV3 | MAP4K4 3127/4885MAPK9 3909/4885CSNK1A1 859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.