Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | DHODH | Q02127 | 1/20 | 0.53 |
| ▸ | F10 | P00742 | 3/20 | 0.53 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | F12 | P00748 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6591721 | 0.89 | P2RX1 (0.64) | MAPTKCNMA1P2RX1KMT2AALDH1A1 | |
| SCHEMBL6591068 | 0.86 | MEN1 (0.55) | MAPTKCNMA1POLBKMT2AALDH1A1 | |
| SCHEMBL5223546 | 0.84 | NPC1 (0.59) | MAPTKMT2AALDH1A1HDAC8 | |
| SCHEMBL890692 | 0.84 | POLB (0.71) | MAPTKCNMA1POLBF10KMT2A | |
| SCHEMBL491720 | 0.83 | POLB (0.51) | MAPTKCNMA1POLBKMT2AALDH1A1 | |
| SCHEMBL1353032 | 0.82 | MEN1 (0.56) | MAPTPOLBDHODHKMT2AALDH1A1 | |
| SCHEMBL1353348 | 0.82 | ALDH1A1 (0.52) | MAPTPOLBF10P2RX1KMT2A | |
| SCHEMBL6594872 | 0.81 | P2RX1 (0.58) | MAPTP2RX1KMT2AALDH1A1KDM1A | |
| SCHEMBL27782904 | 0.81 | KDM1A (0.64) | MAPTKCNMA1P2RX1KMT2AALDH1A1 | |
| SCHEMBL5226448 | 0.80 | MAPT (0.78) | MAPTP2RX1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1143855-C | I (ortho)-anthranilamide derivatives as anti-coagulants | ���ֹɷݹ�˾ | 2004-03-31 | — | — | CN | disclosed |
| EP-1040108-B1 | ORTHO-ANTHRANILAMIDE DERIVATIVES AS ANTI-COAGULANTS | SCHERING AG (DE) | 2004-02-25 | — | — | EP | disclosed |
| US-6498185-B1 | ENZYME FACTOR XA INHIBITORS | BERLEX LABORATORIES, INC. | 2002-12-24 | — | — | US | disclosed |
| US-6380221-B1 | FOR THERAPY OF DISEASE-STATES CHARACTERIZED BY THROMBOTIC ACTIVITY | BERLEX LABORATORIES, INC. | 2002-04-30 | — | — | US | disclosed |
| CN-1282329-A | I (ortho)-anthranilamide derivatives as anti-coagulants | SCHERING AG (DE) | 2001-01-31 | — | — | CN | disclosed |
| US-6140351-A | FOR TREATING THROMBOSIS | BERLEX LABORATORIES, INC. (US) | 2000-10-31 | — | — | US | disclosed |