Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6588202 | 1.00 | KMT2A (0.36) | KMT2APOLBALDH1A1HTTGAA | |
| SCHEMBL6588191 | 1.00 | KMT2A (0.36) | KMT2APOLBALDH1A1HTTGAA | |
| SCHEMBL6590425 | 0.88 | POLB (0.34) | KMT2APOLB | |
| SCHEMBL6586080 | 0.88 | POLB (0.34) | KMT2APOLB | |
| SCHEMBL6586075 | 0.88 | POLB (0.34) | KMT2APOLB | |
| SCHEMBL6590131 | 0.88 | OPRK1 (0.36) | KMT2APOLB | |
| SCHEMBL6588438 | 0.88 | OPRK1 (0.36) | KMT2APOLB | |
| SCHEMBL6588441 | 0.88 | OPRK1 (0.36) | KMT2APOLB | |
| SCHEMBL8506871 | 0.82 | ALDH1A1 (0.37) | KMT2AALDH1A1HTTGAAMAPT | |
| SCHEMBL8506868 | 0.82 | ALDH1A1 (0.37) | KMT2AALDH1A1HTTGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934308-B1 | 3-PYRIDYLOXYMETHYL HETEROCYCLIC ETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LAB (US) | 2004-08-11 | — | — | EP | claimed |