Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 18/20 | 0.49 |
| ▸ | RARB | P10826 | 18/20 | 0.49 |
| ▸ | RARG | P13631 | 17/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6594047 | 0.88 | RARA (0.42) | RARARARBRARG | |
| SCHEMBL6589951 | 0.85 | RARA (0.64) | RARARARBRARG | |
| SCHEMBL6592216 | 0.84 | RARA (0.40) | RARARARBRARGSMN1; SMN2 | |
| SCHEMBL6587113 | 0.80 | RARA (0.60) | RARARARBRARG | |
| SCHEMBL6592120 | 0.80 | RARA (0.52) | RARARARBRARG | |
| SCHEMBL8330182 | 0.79 | RARA (0.47) | RARARARBRARGSMN1; SMN2 | |
| SCHEMBL6590791 | 0.79 | RARA (0.53) | RARARARBRARG | |
| SCHEMBL13784637 | 0.78 | RARA (0.42) | RARARARBRARGSMN1; SMN2FFAR1 | |
| SCHEMBL6588111 | 0.77 | RARA (0.48) | RARARARBRARG | |
| SCHEMBL726359 | 0.76 | RARA (0.60) | RARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042313-B1 | BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES HAVING RETINOID ANTAGONIST LIKE ACTIVITY | ALLERGAN INC (US) | 2004-04-28 | — | — | EP | disclosed |
| EP-1042313-A1 | BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES HAVING RETINOID ANTAGONIST LIKE ACTIVITY | Allergan Sales, Inc. (US) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999033821-A1 | BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES HAVING RETINOID ANTAGONIST-LIKE ACTIVITY | ALLERGAN SALES, INC. (US) | 1999-07-08 | — | — | WO | disclosed |