Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 4/20 | 0.47 |
| ▸ | RARB | P10826 | 4/20 | 0.47 |
| ▸ | RARG | P13631 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8333207 | 0.91 | RARB (0.38) | RARARARBRARGSMN1; SMN2 | |
| SCHEMBL6593199 | 0.79 | RARA (0.49) | RARARARBRARGSMN1; SMN2 | |
| SCHEMBL8331248 | 0.76 | RARB (0.38) | RARARARBRARG | |
| SCHEMBL8329653 | 0.75 | RARA (0.37) | RARARARBRARG | |
| SCHEMBL8328688 | 0.74 | RARA (0.52) | RARARARBRARG | |
| SCHEMBL8329461 | 0.73 | RARA (0.49) | RARARARBRARGIDO1MCL1 | |
| SCHEMBL8329823 | 0.72 | RARA (0.46) | RARARARBRARGIDO1 | |
| SCHEMBL8331802 | 0.69 | RARA (0.52) | RARARARBRARGIDO1MCL1 | |
| SCHEMBL6594047 | 0.69 | RARA (0.42) | RARARARBRARG | |
| SCHEMBL6587113 | 0.68 | RARA (0.60) | RARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958954-A | 2,2-DIALKYL-4-ARYL-SUBSTITUTED BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES | ALLERGAN SALES, INC. (US) | 1999-09-28 | — | — | US | disclosed |