Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | TERT | O14746 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6592661 | 0.80 | TERT (0.46) | ALOX15TERTMEN1KMT2AHSD17B10 | |
| SCHEMBL6593559 | 0.79 | KDM1A (0.39) | KDM4ETERTHSD17B10 | |
| SCHEMBL4073298 | 0.75 | TERT (0.40) | KDM4ETERTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4081931 | 0.74 | TERT (0.37) | TERTRAB9AMAPTNPC1 | |
| SCHEMBL6599297 | 0.72 | TSHR (0.57) | TERTRAB9AMAPTNPC1 | |
| SCHEMBL6593894 | 0.69 | TERT (0.41) | KDM4EL3MBTL1ALOX15TERTMEN1 | |
| SCHEMBL6597299 | 0.69 | ACP1 (0.36) | TERTRAB9ANPC1 | |
| SCHEMBL4076923 | 0.69 | TERT (0.50) | L3MBTL1TERTMEN1KMT2AHSD17B10 | |
| SCHEMBL4073181 | 0.68 | TERT (0.55) | KDM4EALOX15TERTMEN1KMT2A | |
| SCHEMBL6594616 | 0.67 | HPGD (0.36) | KDM4EALOX15TERTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373252-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076975-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | WO | disclosed |