Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | TERT | O14746 | 8/20 | 0.34 |
| ▸ | SPIN1 | Q9Y657 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT5A | Q9NQR1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4081931 | 0.86 | TERT (0.37) | TERTNPC1JAK2RAB9A | |
| SCHEMBL6599297 | 0.75 | TSHR (0.57) | TERTNPC1JAK2RAB9A | |
| SCHEMBL4076910 | 0.71 | BRD4 (0.35) | NTSR1TERT | |
| SCHEMBL6592661 | 0.70 | TERT (0.46) | TERT | |
| SCHEMBL6593597 | 0.69 | KDM4E (0.44) | TERTNPC1RAB9A | |
| SCHEMBL6593559 | 0.69 | KDM1A (0.39) | TERT | |
| SCHEMBL4074853 | 0.67 | HRH4 (0.40) | TERT | |
| SCHEMBL4081462 | 0.67 | HTR1A (0.35) | HRH1TERT | |
| SCHEMBL4081927 | 0.67 | ABCC1 (0.34) | NTSR1TERT | |
| SCHEMBL6592900 | 0.67 | TERT (0.33) | TERTNPC1JAK2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373252-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-01-02 | — | — | EP | claimed |
| WO-2002076975-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | WO | claimed |
| EP-1373252-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076975-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | WO | disclosed |