Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 11/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.59 |
| ▸ | MAOA | P21397 | 2/20 | 0.59 |
| ▸ | MAOB | P27338 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.58 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6594093 | 1.00 | HPGD (0.59) | HPGDPTPN1MAOAMAOBPOLB | |
| SCHEMBL6597189 | 1.00 | HPGD (0.59) | HPGDPTPN1MAOAMAOBPOLB | |
| SCHEMBL6598986 | 1.00 | HPGD (0.59) | HPGDPTPN1MAOAMAOBPOLB | |
| SCHEMBL6596341 | 0.89 | HPGD (0.63) | HPGDPTPN1MAOAMAOBPOLB | |
| SCHEMBL6597460 | 0.89 | HPGD (0.63) | HPGDPTPN1MAOAMAOBPOLB | |
| SCHEMBL6597588 | 0.84 | KDM4E (0.52) | — | |
| SCHEMBL6595873 | 0.84 | GPR119 (0.66) | HPGDPTPN1MAOAMAOBPOLB | |
| SCHEMBL6595876 | 0.84 | GPR119 (0.66) | HPGDPTPN1MAOAMAOBPOLB | |
| SCHEMBL6598492 | 0.80 | PPARG (0.52) | HPGD | |
| SCHEMBL6598250 | 0.80 | PPARG (0.52) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0981526-B1 | NOVEL ANTIDIABETIC COMPOUNDS HAVING HYPOLIPIDAEMIC, ANTIHYPERTENSIVE PROPERTIES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | REDDYS LAB LTD DR (IN) | 2004-02-25 | — | — | EP | claimed |
| EP-0981526-B1 | NOVEL ANTIDIABETIC COMPOUNDS HAVING HYPOLIPIDAEMIC, ANTIHYPERTENSIVE PROPERTIES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | REDDYS LAB LTD DR (IN) | 2004-02-25 | — | — | EP | disclosed |