Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.66 |
| ▸ | HPGD | P15428 | 13/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.61 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6595876 | 1.00 | GPR119 (0.66) | GPR119HPGDPTPN1POLBMAOA | |
| SCHEMBL6597308 | 0.87 | GPR119 (0.76) | GPR119HPGDPTPN1POLBMAOA | |
| SCHEMBL6595334 | 0.87 | GPR119 (0.76) | GPR119HPGDPTPN1POLBMAOA | |
| SCHEMBL6597189 | 0.84 | HPGD (0.59) | GPR119HPGDPTPN1POLBMAOA | |
| SCHEMBL6594093 | 0.84 | HPGD (0.59) | GPR119HPGDPTPN1POLBMAOA | |
| SCHEMBL6598986 | 0.84 | HPGD (0.59) | GPR119HPGDPTPN1POLBMAOA | |
| SCHEMBL6594097 | 0.84 | HPGD (0.59) | GPR119HPGDPTPN1POLBMAOA | |
| SCHEMBL6593704 | 0.83 | SMN1; SMN2 (0.56) | GPR119 | |
| SCHEMBL6597460 | 0.83 | HPGD (0.63) | GPR119HPGDPTPN1POLBMAOA | |
| SCHEMBL6596341 | 0.83 | HPGD (0.63) | GPR119HPGDPTPN1POLBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0981526-B1 | NOVEL ANTIDIABETIC COMPOUNDS HAVING HYPOLIPIDAEMIC, ANTIHYPERTENSIVE PROPERTIES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | REDDYS LAB LTD DR (IN) | 2004-02-25 | — | — | EP | claimed |
| EP-0981526-A1 | NOVEL ANTIDIABETIC COMPOUNDS HAVING HYPOLIPIDAEMIC, ANTIHYPERTENSIVE PROPERTIES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-03-01 | — | — | EP | claimed |
| WO-1997041119-A1 | NOVEL ANTIDIABETIC COMPOUNDS HAVING HYPOLIPIDAEMIC, ANTIHYPERTENSIVE PROPERTIES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1997-11-06 | — | — | WO | claimed |