Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.47 |
| ▸ | CTSV | O60911 | 3/20 | 0.44 |
| ▸ | CTSL | P07711 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6594148 | 1.00 | CYP19A1 (0.47) | CYP19A1CYP11B1CYP11B2CTSVCTSL | |
| SCHEMBL6080467 | 0.90 | CYP19A1 (0.44) | CYP19A1CYP11B1CYP11B2CTSVCTSL | |
| SCHEMBL6590323 | 0.86 | CTSV (0.44) | CYP19A1CTSVCTSLPTGER1APP | |
| SCHEMBL6590313 | 0.86 | CTSV (0.44) | CYP19A1CTSVCTSLPTGER1APP | |
| SCHEMBL6594071 | 0.84 | ALDH1A1 (0.47) | MEN1KMT2AMAPTPOLBTDP1 | |
| SCHEMBL6594082 | 0.84 | ALDH1A1 (0.47) | MEN1KMT2AMAPTPOLBTDP1 | |
| SCHEMBL6590202 | 0.82 | CTSV (0.43) | CYP19A1CTSVCTSLAPPMCL1 | |
| SCHEMBL6590188 | 0.82 | CTSV (0.43) | CYP19A1CTSVCTSLAPPMCL1 | |
| SCHEMBL6592928 | 0.81 | CTSV (0.47) | CYP19A1CTSVCTSLPTGER1APP | |
| SCHEMBL6592924 | 0.81 | CTSV (0.47) | CYP19A1CTSVCTSLPTGER1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |