Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 10/20 | 0.45 |
| ▸ | CTSK | P43235 | 10/20 | 0.45 |
| ▸ | CTSS | P25774 | 10/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6592517 | 0.92 | CTSL (0.40) | CTSLCTSKCTSS | |
| SCHEMBL6590240 | 0.92 | CTSL (0.38) | CTSLCTSKCTSSCTSBNFKB1 | |
| SCHEMBL6595149 | 0.90 | CTSL (0.57) | CTSLCTSKCTSS | |
| SCHEMBL6591350 | 0.90 | CTSK (0.37) | CTSLCTSKCTSSCTSBNFKB1 | |
| SCHEMBL6589756 | 0.88 | CTSK (0.38) | CTSLCTSKCTSSCTSB | |
| SCHEMBL6594449 | 0.87 | CTSK (0.33) | CTSLCTSKCTSSCTSB | |
| SCHEMBL6592550 | 0.87 | CTSK (0.37) | CTSLCTSKCTSSCTSB | |
| SCHEMBL6591380 | 0.86 | CTSK (0.35) | CTSLCTSKCTSSCTSB | |
| SCHEMBL6594541 | 0.85 | CTSL (0.32) | CTSLCTSKCTSS | |
| SCHEMBL6591637 | 0.85 | CTSL (0.47) | CTSLCTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178986-B1 | FURANONE DERIVATIVES AS INHIBITORS OF CATHEPSIN S | MEDIVIR UK LTD (GB) | 2004-02-25 | — | — | EP | claimed |