Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.53 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.52 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4906777 | 0.90 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPK1HCRTR1HCRTR2KMT2A | |
| SCHEMBL6171032 | 0.88 | SMN1; SMN2 (0.53) | SMN1; SMN2KMT2AALDH1A1ALOX15HSD17B10 | |
| SCHEMBL2781032 | 0.86 | SMN1; SMN2 (0.55) | SMN1; SMN2MAPK1HCRTR1HCRTR2KMT2A | |
| SCHEMBL2248724 | 0.85 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPK1HCRTR1HCRTR2KMT2A | |
| SCHEMBL221971 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPK1HCRTR1HCRTR2KMT2A | |
| SCHEMBL2252952 | 0.85 | ALDH1A1 (0.61) | SMN1; SMN2MAPK1HCRTR1HCRTR2KMT2A | |
| SCHEMBL20496747 | 0.83 | MAPK1 (0.55) | SMN1; SMN2MAPK1HCRTR1HCRTR2KMT2A | |
| SCHEMBL1421327 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2MAPK1HCRTR1HCRTR2KMT2A | |
| Hydrochloric Acid SCHEMBL6596688 | 0.83 | CYP2A13 (0.54) | KMT2AALDH1A1ALOX15HSD17B10HPGD | |
| SCHEMBL20496749 | 0.82 | ALDH1A1 (0.64) | SMN1; SMN2MAPK1HCRTR1HCRTR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863755-B1 | ANTITHROMBOTIC DIAMINES | LILLY CO ELI (US) | 2004-12-15 | — | — | EP | disclosed |
| US-6265575-B1 | THROMBIN INHIBITORS | ELI LILLY AND COMPANY | 2001-07-24 | — | — | US | disclosed |
| US-6251921-B1 | ADMINISTERING THROMBIN INHIBITING DIAMINE COMPOUND TO MAMMAL | ELI LILLY AND COMPANY | 2001-06-26 | — | — | US | disclosed |
| US-6025382-A | Antithrombotic diamines | ELI LILLY AND COMPANY (US) | 2000-02-15 | — | — | US | disclosed |
| EP-0863755-A4 | ANTITHROMBOTIC DIAMINES | LILLY CO ELI (US) | 1999-01-20 | — | — | EP | disclosed |
| EP-0863755-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997025033-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |